--- product_id: 14345228 title: "Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings" brand: "thorne" price: "β‚Ή 10879" currency: INR in_stock: true reviews_count: 12 category: "Thorne" url: https://www.desertcart.in/products/14345228-methyl-guard-plus-active-folate-5-mthf-with-vitamins-b2 store_origin: IN region: India --- # Methylcobalamin B12 for optimal absorption 4 rounds of rigorous purity & potency testing Active 5-MTHF folate for superior methylation Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings **Brand:** thorne **Price:** β‚Ή 10879 **Availability:** βœ… In Stock ## Summary > 🧠 Elevate your wellness game with methylation mastery! ## Quick Answers - **What is this?** Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings by thorne - **How much does it cost?** β‚Ή 10879 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.in](https://www.desertcart.in/products/14345228-methyl-guard-plus-active-folate-5-mthf-with-vitamins-b2) ## Best For - thorne enthusiasts ## Why This Product - Trusted thorne brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - β€’ **Brain & Heart Synergy:** Supports cardiovascular health and cognitive function by enhancing neurotransmitter production and cellular energy. - β€’ **Clean & Allergen-Free:** Gluten, dairy, soy, fish, and shellfish-freeβ€”perfect for the mindful professional avoiding common allergens without compromise. - β€’ **Tested for Excellence:** Each batch undergoes 4 rounds of state-of-the-art testing, guaranteeing purity, potency, and shelf-life stability for your peace of mind. - β€’ **Clinically Trusted Formula:** Chosen by 100+ pro sports teams and top healthcare practitioners, ensuring elite-grade quality and efficacy you can rely on. - β€’ **Precision Methylation Support:** Harness the power of active folate (5-MTHF) and methylated B vitamins to optimize your body's methylation pathways and maintain healthy homocysteine levels. ## Overview THORNE Methyl-Guard Plus delivers a potent blend of active folate (5-MTHF), methylcobalamin (B12), and essential B vitamins designed to optimize methylation and support healthy homocysteine levels. This gluten, dairy, and soy-free formula is rigorously tested in 4 stages to ensure purity and potency, trusted by professional athletes and healthcare experts alike to promote cardiovascular and brain health. ## Description Buy THORNE - Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings on desertcart.com βœ“ FREE SHIPPING on qualified orders Review: MTHFR - High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, I’m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues. Review: Vitamins - Great vitamins that give good energy ## Features - Healthy Methylation: Provides B vitamins and other nutrients that optimize methylation and promote a healthy level of homocysteine in the bloodsteam* - Active Forms: Formulated with superior methyl donors, including betaine and active folate (5-MTHF) and B12 (as methylcobalamin), to optimize utilization in the body - Heart and Brain Benefits: Sustains cardiovascular health and promotes healthy brain function by supporting neurotransmitter production and enhancing cellular energy levels* - 4 Rounds of Testing: Our state-of-the-art laboratories enable us to conduct 4 rounds of testing on every product, from analyzing the purity of raw materials to confirming the shelf life of finished formulas - Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey) ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B00O5AHC4S | | ASIN | B00O5AHC4S | | Age Range Description | Adult | | Allergen Information | Dairy Free, Fish Free, Shellfish Free, Soy Free | | Best Sellers Rank | #5,763 in Health & Household ( See Top 100 in Health & Household ) #103 in Blended Vitamin & Mineral Supplements #570 in Diet & Sports Nutrition | | Brand Name | THORNE | | Color | Translucent Light Yellow | | Container Type | Bottle | | Customer Reviews | 4.7 4.7 out of 5 stars (1,735) | | Date First Available | March 8, 2011 | | Department | All Ages | | Diet Type | Gluten Free | | Dosage Form | Capsule | | Flavor | Unflavored | | Global Trade Identification Number | 00693749789017 | | Is Discontinued By Manufacturer | No | | Item Dimensions | 2.38 x 2.38 x 4.23 inches | | Item Form | Capsule | | Item Weight | 3.84 ounces | | Item model number | No Model | | Manufacturer | Thorne Research | | Manufacturer | Thorne Research | | Manufacturer Part Number | SF789 | | Model Name | e Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6, and B12 - Supports methylation and Healthy Level of homocysteine - Gluten-Free, Dairy-Free, Soy-Free - 9 | | Model Number | No Model | | Number of Items | 1 | | Primary Supplement Type | B-Complex | | Product Benefits | Cardiovascular Health Support | | Product Dimensions | 2.38 x 2.38 x 4.23 inches; 3.84 ounces | | Special Ingredients | Betaine, 5-MTHF, Riboflavin 5'-phosphate, Pyridoxal 5'-phosphate, Methylcobalamin | | Specific Uses For Product | Bone, Heart | | Supplement Formulation | Individual Supplement | | UPC | 693749789017 701627510421 884967152206 882855267766 885786045052 | | Unit Count | 90 Count | ## Product Details - **Brand:** THORNE - **Diet Type:** Gluten Free - **Flavor:** Unflavored - **Item Form:** Capsule - **Primary Supplement Type:** B-Complex ## Images ![Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings - Image 1](https://m.media-amazon.com/images/I/61BtsSBpN9L.jpg) ## Questions & Answers **Q: What is the difference between "methyl-guard" and "methyl-guard plus" products?** A: Methyl Guard plus is stronger. The Methyl Guard Plus contains about twice as much b12 (3mg vs 1.2mg), about twice as much folate (3mg vs 1.2mg), about twice as much b6 (45mg vs 20.4mg) and contains Riboflavin. **Q: Why doesn't it show the label, I'm not going to pay this amount for something without knowing what and how much is in it!** A: If you look at the selection of pictures to right of the bottle the bottom picture includes the label. You can click on that image to show it larger. **Q: are these capsules enteric coated? taking pyridoxal-5-phosphate without enteric coating useless** A: Not coated. Just a vegetarian capsule. For me, my body has been starved of these active forms of B vitamins that it's anything but useless. If you want to encourage it not to digest as quickly, a trick my doctor tells me to do (with fish oil for example) is to freeze the capsule so that it takes longer to digest. You can look for the specific forms of active B vitamins to find them enteric coated. Details on the product: https://www.thorne.com/products/dp/methyl-guard-plus-reg **Q: Does this turn your stools orange colored?** A: Orange stools may signify you are dumping copper. Look up un bound copper, bioavailable copper and copper toxicity. You need boron and vit K2. ## Customer Reviews ### ⭐⭐⭐⭐⭐ MTHFR *by J***N on October 12, 2025* High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, I’m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues. ### ⭐⭐⭐⭐⭐ Vitamins *by S***E on March 16, 2026* Great vitamins that give good energy ### ⭐⭐⭐⭐⭐ One of the best out there! *by A***R on March 7, 2026* I've been using Methyl-Guard for well over a year in conjunction with many other Thorne products. I am very pleased with the results both physically and cognitively. ## Frequently Bought Together - THORNE Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules - THORNE Magnesium CitraMate - Magnesium Supplement with Citrate-Malate - Support Heart, Skeletal Muscles, Cardiac, Lung Function, and Bone Density* - Gluten-Free, Dairy-Free, Soy-Free - 90 Capsules - THORNE Vitamin D-5000 - Vitamin D3 Supplement - Support Healthy Bones, Teeth, Muscles, Cardiovascular, and Immune Function* - NSF Certified for Sport - Dairy-Free, Soy-Free - 60 Capsules --- ## Why Shop on Desertcart? - πŸ›’ **Trusted by 1.3+ Million Shoppers** β€” Serving international shoppers since 2016 - 🌍 **Shop Globally** β€” Access 737+ million products across 21 categories - πŸ’° **No Hidden Fees** β€” All customs, duties, and taxes included in the price - πŸ”„ **15-Day Free Returns** β€” Hassle-free returns (30 days for PRO members) - πŸ”’ **Secure Payments** β€” Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** β€” Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.in/products/14345228-methyl-guard-plus-active-folate-5-mthf-with-vitamins-b2](https://www.desertcart.in/products/14345228-methyl-guard-plus-active-folate-5-mthf-with-vitamins-b2) --- *Product available on Desertcart India* *Store origin: IN* *Last updated: 2026-05-03*