---
product_id: 14345228
title: "THORNE - Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings"
brand: "thorne"
price: "₹ 11085"
currency: INR
in_stock: true
reviews_count: 12
category: "Thorne"
url: https://www.desertcart.in/products/14345228-thorne-methyl-guard-plus-active-folate-5-mthf-with-vitamins
store_origin: IN
region: India
---

# Methylcobalamin B12 for optimal absorption 4 rounds of rigorous purity & potency testing Active 5-MTHF folate for superior methylation THORNE - Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings

**Brand:** thorne
**Price:** ₹ 11085
**Availability:** ✅ In Stock

## Summary

> 🧠 Elevate your wellness game with methylation mastery!

## Quick Answers

- **What is this?** THORNE - Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings by thorne
- **How much does it cost?** ₹ 11085 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.in](https://www.desertcart.in/products/14345228-thorne-methyl-guard-plus-active-folate-5-mthf-with-vitamins)

## Best For

- thorne enthusiasts

## Why This Product

- Trusted thorne brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Brain & Heart Synergy:** Supports cardiovascular health and cognitive function by enhancing neurotransmitter production and cellular energy.
- • **Clean & Allergen-Free:** Gluten, dairy, soy, fish, and shellfish-free—perfect for the mindful professional avoiding common allergens without compromise.
- • **Tested for Excellence:** Each batch undergoes 4 rounds of state-of-the-art testing, guaranteeing purity, potency, and shelf-life stability for your peace of mind.
- • **Clinically Trusted Formula:** Chosen by 100+ pro sports teams and top healthcare practitioners, ensuring elite-grade quality and efficacy you can rely on.
- • **Precision Methylation Support:** Harness the power of active folate (5-MTHF) and methylated B vitamins to optimize your body's methylation pathways and maintain healthy homocysteine levels.

## Overview

THORNE Methyl-Guard Plus delivers a potent blend of active folate (5-MTHF), methylcobalamin (B12), and essential B vitamins designed to optimize methylation and support healthy homocysteine levels. This gluten, dairy, and soy-free formula is rigorously tested in 4 stages to ensure purity and potency, trusted by professional athletes and healthcare experts alike to promote cardiovascular and brain health.

## Description

Foundational Wellness Visit the Store Foundational Wellness Visit the Store Sports Nutrition Visit the Store Sports Nutrition

Review: MTHFR - High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, I’m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues.
Review: Vitamins - Great vitamins that give good energy

## Features

- Healthy Methylation: Provides B vitamins and other nutrients that optimize methylation and promote a healthy level of homocysteine in the bloodstream*
- Active Forms: Formulated with superior methyl donors, including betaine and active folate (5-MTHF) and B12 (as methylcobalamin), to optimize utilization in the body
- Heart and Brain Benefits: Sustains cardiovascular health and promotes healthy brain function by supporting neurotransmitter production and enhancing cellular energy levels*
- 4 Rounds of Testing: Our state-of-the-art laboratories enable us to conduct 4 rounds of testing on every product, from analyzing the purity of raw materials to confirming the shelf life of finished formulas
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00O5AHC4S |
| Age Range Description | Adult |
| Allergen Information | Dairy Free, Fish Free, Shellfish Free, Soy Free |
| Best Sellers Rank | #5,818 in Health & Household ( See Top 100 in Health & Household ) #101 in Blended Vitamin & Mineral Supplements #586 in Diet & Sports Nutrition |
| Brand | THORNE |
| Brand Name | THORNE |
| Color | Translucent Light Yellow |
| Container Type | Bottle |
| Customer Reviews | 4.7 out of 5 stars 1,746 Reviews |
| Diet Type | Gluten Free |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Global Trade Identification Number | 00693749789017 |
| Item Dimensions | 2.38 x 2.38 x 4.23 inches |
| Item Form | Capsule |
| Item Weight | 0.24 Pounds |
| Manufacturer | Thorne Research |
| Manufacturer Part Number | SF789 |
| Material Features | Vegetarian |
| Model Name | e Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6, and B12 - Supports methylation and Healthy Level of homocysteine - Gluten-Free, Dairy-Free, Soy-Free - 9 |
| Model Number | No Model |
| Number of Items | 1 |
| Primary Supplement Type | B-Complex |
| Product Benefits | Cardiovascular Health Support |
| Special Ingredients | Betaine, 5-MTHF, Riboflavin 5'-phosphate, Pyridoxal 5'-phosphate, Methylcobalamin |
| Specific Uses For Product | Bone, Heart |
| Supplement Formulation | Individual Supplement |
| UPC | 693749789017 701627510421 884967152206 882855267766 885786045052 |
| Unit Count | 90 Count |

## Product Details

- **Brand:** THORNE
- **Diet Type:** Gluten Free
- **Flavor:** Unflavored
- **Item Form:** Capsule
- **Primary Supplement Type:** B-Complex

## Images

![THORNE - Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings - Image 1](https://m.media-amazon.com/images/I/61BtsSBpN9L.jpg)
![THORNE - Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings - Image 2](https://m.media-amazon.com/images/I/71BAfUG+4kL.jpg)
![THORNE - Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings - Image 3](https://m.media-amazon.com/images/I/81sv9I+C-lL.jpg)
![THORNE - Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings - Image 4](https://m.media-amazon.com/images/I/81D+ZcIXj7L.jpg)
![THORNE - Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings - Image 5](https://m.media-amazon.com/images/I/811gbkcjWxL.jpg)

## Questions & Answers

**Q: What makes Thorne supplements high quality?**
A: Thorne produces high-quality supplements through rigorous testing, well-researched ingredient sourcing, and strict manufacturing standards. We avoid unnecessary additives, binders, and fillers that may interfere with nutrient absorption.

**Q: How does Thorne test its supplements for quality?**
A: To confirm the purity of our ingredients, the potency of our formulas, and the absence of all contaminants, we carry out a minimum of four rounds of testing on every product we manufacture. 100+ Thorne employees are dedicated to ensuring quality.

**Q: Are Thorne supplements clinically tested and safe?**
A: Thorne partners with researchers and conducts clinical trials to support the efficacy of our products. Our team of doctors and medical experts substantiate each ingredient in every formula based on extensive clinical research and medical literature.

**Q: Why are Thorne products more expensive than other supplements?**
A: When it comes to the health of our customers, we never settle. Thorne products may be priced higher than some others because of our commitment to quality at every step. We don’t simply meet the standard in dietary supplements — we set the standard.

**Q: Where are Thorne supplements made and where are the ingredients sourced from?**
A: Located in South Carolina, Thorne manufactures supplements in the USA using globally sourced ingredients. When it comes to ingredient sourcing, we seek out only the highest-quality ingredients, selecting each one for its purity and effectiveness.

## Customer Reviews

### ⭐⭐⭐⭐⭐ MTHFR
*by J***N on October 12, 2025*

High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, I’m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues.

### ⭐⭐⭐⭐⭐ Vitamins
*by S***E on March 16, 2026*

Great vitamins that give good energy

### ⭐⭐⭐⭐⭐ Excellent product, very effective in delivery of methylated B vitamins and Bromaine/TMG
*by M***C on February 2, 2026*

Great product, contains Betaine?TMG too which is essential for proper maintenance of homocysteine levels.

## Frequently Bought Together

- THORNE Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules
- THORNE Magnesium CitraMate - Magnesium Supplement with Citrate-Malate - Support Heart, Skeletal Muscles, Cardiac, Lung Function, and Bone Density* - Gluten-Free, Dairy-Free, Soy-Free - 90 Capsules
- THORNE Vitamin D-5000 - Vitamin D3 Supplement - Support Healthy Bones, Teeth, Muscles, Cardiovascular, and Immune Function* - NSF Certified for Sport - Dairy-Free, Soy-Free - 60 Capsules

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---

*Product available on Desertcart India*
*Store origin: IN*
*Last updated: 2026-05-25*