--- product_id: 253690400 title: "Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings" brand: "thorne" price: "ā‚¹ 12264" currency: INR in_stock: true reviews_count: 5 category: "Thorne" url: https://www.desertcart.in/products/253690400-methyl-guard-plus-active-folate-5-mthf-with-vitamins-b2 store_origin: IN region: India --- # Methylcobalamin B12 for superior absorption 4 rounds of rigorous purity & potency testing 5-MTHF active folate for optimal methylation Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings **Brand:** thorne **Price:** ā‚¹ 12264 **Availability:** āœ… In Stock ## Summary > šŸ§¬ Elevate your wellness game with the methylation masterclass! ## Quick Answers - **What is this?** Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings by thorne - **How much does it cost?** ā‚¹ 12264 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.in](https://www.desertcart.in/products/253690400-methyl-guard-plus-active-folate-5-mthf-with-vitamins-b2) ## Best For - thorne enthusiasts ## Why This Product - Trusted thorne brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - ā€¢ **Neuro & Heart Synergy:** Supports cardiovascular health and brain function by enhancing neurotransmitter production and cellular energy. - ā€¢ **Clean & Pure Assurance:** Gluten, dairy, and soy-free with 4 rounds of lab testing guaranteeing purity and potency in every capsule. - ā€¢ **Millennial-Ready Wellness:** Unflavored, easy-to-take capsules designed for busy professionals prioritizing peak health and longevity. - ā€¢ **Clinically Trusted Formula:** Chosen by 100+ pro sports teams and top healthcare practitioners, ensuring elite-grade quality and efficacy. - ā€¢ **Precision Methylation Support:** Harness the power of active folate (5-MTHF) and methyl donors to optimize your body's methylation process and maintain healthy homocysteine levels. ## Overview THORNE Methyl-Guard Plus delivers active folate (5-MTHF) alongside vitamins B2, B6, and methylcobalamin B12 to support healthy methylation and maintain optimal homocysteine levels. Backed by rigorous 4-stage testing and trusted by elite athletes and healthcare pros, this gluten, dairy, and soy-free formula promotes cardiovascular and brain health, making it a top-tier choice for adults seeking advanced nutritional support. ## Description THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings : desertcart.ae: Automotive Review: High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, Iā€™m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues. Review: Recently I found out Iā€™m anemic and distant to go on medication so I did my research and found this to have all the things I need. ## Features - Healthy Methylation: Provides B vitamins and other nutrients that optimize methylation and promote a healthy level of homocysteine in the bloodsteam* - Active Forms: Formulated with superior methyl donors, including betaine and active folate (5-MTHF) and B12 (as methylcobalamin), to optimize utilization in the body - Heart and Brain Benefits: Sustains cardiovascular health and promotes healthy brain function by supporting neurotransmitter production and enhancing cellular energy levels* - 4 Rounds of Testing: Our state-of-the-art laboratories enable us to conduct 4 rounds of testing on every product, from analyzing the purity of raw materials to confirming the shelf life of finished formulas - Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey) ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B00O5AHC4S | | ASIN | B00O5AHC4S | | Age Range Description | Adult | | Best Sellers Rank | #988 in Health ( See Top 100 in Health ) #18 in Multivitamins Nutritional Supplements | | Brand Name | THORNE | | Color | red | | Country of Publication | USA | | Country of origin | USA | | Customer Reviews | 4.7 4.7 out of 5 stars (1,637) | | Customer reviews | 4.7 4.7 out of 5 stars (1,637) | | Diet Type | Gluten Free | | Dosage Form | Capsule | | Flavor | Unflavored | | Global Trade Identification Number | 00693749789017 | | Is Discontinued By Manufacturer | No | | Item Dimensions | 6 x 6 x 10.7 centimeters | | Item Form | Capsule | | Item Weight | 0.24 Pounds | | Item model number | No Model | | Manufacturer | Thorne Research | | Manufacturer | Thorne Research | | Manufacturer Part Number | SF789 | | Material Type Free | en_AE | | Model Name | Methyl-Guard Plus | | Model Number | No Model | | Number of Items | 1 | | Primary Supplement Type | Riboflavin | | Product Benefits | Eye Health | | Product Dimensions | 6.05 x 6.05 x 10.74 cm; 108.86 g | | Specific Uses For Product | Heart | | UPC | 693749789017 701627510421 884967152206 882855267766 885786045052 | | Unit Count | 90.0 Count | ## Product Details - **Brand:** THORNE - **Diet type:** Gluten Free - **Flavour:** Unflavored - **Item form:** Capsule - **Primary supplement type:** Riboflavin ## Images ![Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings - Image 1](https://m.media-amazon.com/images/I/611fI5u7HYL.jpg) ## Available Options This product comes in different **Style** options. ## Questions & Answers **Q: What is the difference between "methyl-guard" and "methyl-guard plus" products?** A: Methyl Guard plus is stronger. The Methyl Guard Plus contains about twice as much b12 (3mg vs 1.2mg), about twice as much folate (3mg vs 1.2mg), about twice as much b6 (45mg vs 20.4mg) and contains Riboflavin. **Q: Why doesn't it show the label, I'm not going to pay this amount for something without knowing what and how much is in it!** A: If you look at the selection of pictures to right of the bottle the bottom picture includes the label. You can click on that image to show it larger. **Q: are these capsules enteric coated? taking pyridoxal-5-phosphate without enteric coating useless** A: Not coated. Just a vegetarian capsule. For me, my body has been starved of these active forms of B vitamins that it's anything but useless. If you want to encourage it not to digest as quickly, a trick my doctor tells me to do (with fish oil for example) is to freeze the capsule so that it takes longer to digest. You can look for the specific forms of active B vitamins to find them enteric coated. Details on the product: https://www.thorne.com/products/dp/methyl-guard-plus-reg **Q: Does this turn your stools orange colored?** A: Orange stools may signify you are dumping copper. Look up un bound copper, bioavailable copper and copper toxicity. You need boron and vit K2. ## Customer Reviews ### ā­ā­ā­ā­ā­ Review *by J***N on 12 October 2025* High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, Iā€™m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues. ### ā­ā­ā­ā­ā­ Review *by L***. on 25 February 2025* Recently I found out Iā€™m anemic and distant to go on medication so I did my research and found this to have all the things I need. ### ā­ā­ā­ā­ā­ Review *by S***E on 16 March 2026* Great vitamins that give good energy ## Frequently Bought Together - THORNE Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules - THORNE Magnesium CitraMate - Magnesium Supplement with Citrate-Malate - Support Heart, Skeletal Muscles, Cardiac, Lung Function, and Bone Density* - Gluten-Free, Dairy-Free, Soy-Free - 90 Capsules - THORNE Vitamin D-5000 - Vitamin D3 Supplement - Support Healthy Bones, Teeth, Muscles, Cardiovascular, and Immune Function* - NSF Certified for Sport - Dairy-Free, Soy-Free - 60 Capsules --- ## Why Shop on Desertcart? - šŸ›’ **Trusted by 1.3+ Million Shoppers** ā€” Serving international shoppers since 2016 - šŸŒ **Shop Globally** ā€” Access 737+ million products across 21 categories - šŸ’° **No Hidden Fees** ā€” All customs, duties, and taxes included in the price - šŸ”„ **15-Day Free Returns** ā€” Hassle-free returns (30 days for PRO members) - šŸ”’ **Secure Payments** ā€” Trusted payment options with buyer protection - ā­ **TrustPilot Rated 4.5/5** ā€” Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.in/products/253690400-methyl-guard-plus-active-folate-5-mthf-with-vitamins-b2](https://www.desertcart.in/products/253690400-methyl-guard-plus-active-folate-5-mthf-with-vitamins-b2) --- *Product available on Desertcart India* *Store origin: IN* *Last updated: 2026-05-13*