---
product_id: 253690400
title: "THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings"
brand: "thorne"
price: "₹ 9920"
currency: INR
in_stock: true
reviews_count: 5
category: "Thorne"
url: https://www.desertcart.in/products/253690400-thorne-methyl-guard-plus-active-folate-5-mthf-with-vitamins
store_origin: IN
region: India
---

# 90 capsules = 30 daily servings 5-MTHF active folate for optimal methylation Supports heart & brain health THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings

**Brand:** thorne
**Price:** ₹ 9920
**Availability:** ✅ In Stock

## Summary

> 🧠💥 Unlock your body's full potential with Methyl-Guard Plus — because optimal health waits for no one!

## Quick Answers

- **What is this?** THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings by thorne
- **How much does it cost?** ₹ 9920 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.in](https://www.desertcart.in/products/253690400-thorne-methyl-guard-plus-active-folate-5-mthf-with-vitamins)

## Best For

- thorne enthusiasts

## Why This Product

- Trusted thorne brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Endorsed by Champions:** Chosen by 100+ pro sports teams and top healthcare practitioners for peak performance and wellness.
- • **Clinically Trusted Quality:** 4 rounds of rigorous testing guarantee purity and potency you can rely on.
- • **Clean & Allergen-Free Formula:** Gluten, dairy, and soy-free to fit your clean-living lifestyle without compromise.
- • **Precision Methylation Support:** Active folate (5-MTHF) and methylcobalamin B12 ensure superior nutrient absorption and utilization.
- • **Holistic Cardiovascular & Cognitive Boost:** Formulated to sustain heart health and enhance brain function through neurotransmitter support.

## Overview

Methyl-Guard Plus delivers a potent blend of active folate (5-MTHF), methylcobalamin B12, and essential B vitamins designed to optimize methylation and maintain healthy homocysteine levels. This gluten, dairy, and soy-free formula supports cardiovascular and brain health, backed by rigorous 4-stage testing and trusted by elite athletes and healthcare professionals alike. With 90 capsules providing 30 servings, it’s a clean, clinically validated choice for proactive wellness.

## Description

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Review: MTHFR - High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, I’m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues.
Review: Just what the doctor ordered! - Recently I found out I’m anemic and distant to go on medication so I did my research and found this to have all the things I need.

## Features

- Healthy Methylation: Provides B vitamins and other nutrients that optimize methylation and promote a healthy level of homocysteine in the bloodsteam
- Active Forms: Formulated with superior methyl donors, including betaine and active folate (5-MTHF) and B12 (as methylcobalamin), to optimize utilization in the body
- Heart and Brain Benefits: Sustains cardiovascular health and promotes healthy brain function by supporting neurotransmitter production and enhancing cellular energy levels
- 4 Rounds of Testing: Our state-of-the-art laboratories enable us to conduct 4 rounds of testing on every product, from analyzing the purity of raw materials to confirming the shelf life of finished formulas
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the 1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00O5AHC4S |
| Age Range Description | Adult |
| Best Sellers Rank | #2,768 in Health ( See Top 100 in Health ) #60 in Multivitamins Nutritional Supplements |
| Brand | THORNE |
| Brand Name | THORNE |
| Color | red |
| Country of Publication | USA |
| Customer Reviews | 4.7 out of 5 stars 1,664 Reviews |
| Diet Type | Gluten Free |
| Dosage Form | Capsules |
| Flavor | Unflavored |
| Flavour | Unflavored |
| Global Trade Identification Number | 00693749789017 |
| Item Dimensions | 6 x 6 x 10.7 centimeters |
| Item Form | Capsule |
| Item Weight | 0.24 Pounds |
| Item form | Capsule |
| Item weight | 0.24 Pounds |
| Manufacturer | Thorne Research |
| Manufacturer Part Number | SF789 |
| Material Features | Dairy Free, Gluten Free |
| Material Type Free | en_AE |
| Model Name | SF789 |
| Model Number | No Model |
| Number of Items | 1 |
| Primary Supplement Type | Riboflavin |
| Primary supplement type | Riboflavin |
| Product Benefits | Brain Health Support, Energy Management, Heart Health Support, Nerve Support |
| Specific Uses For Product | Heart |
| UPC | 693749789017 701627510421 884967152206 882855267766 885786045052 |
| Unit Count | 90.0 Count |
| Unit count | 90.0 Count |

## Product Details

- **Age range (description):** Adult
- **Brand:** THORNE
- **Diet type:** Gluten Free
- **Flavour:** Unflavored
- **Item dimensions L x W x H:** 6 x 6 x 10.7 centimeters
- **Item form:** Capsule
- **Item weight:** 0.24 Pounds
- **Primary supplement type:** Riboflavin
- **Product benefits:** Eye Health
- **Unit count:** 90.0 Count

## Images

![THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings - Image 1](https://m.media-amazon.com/images/I/611fI5u7HYL.jpg)
![THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings - Image 2](https://m.media-amazon.com/images/I/71+ttyxERbL.jpg)
![THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings - Image 3](https://m.media-amazon.com/images/I/71+mLMs9inL.jpg)
![THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings - Image 4](https://m.media-amazon.com/images/I/81kXNNJzXaL.jpg)
![THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings - Image 5](https://m.media-amazon.com/images/I/61kxlFQHo2L.jpg)

## Available Options

This product comes in different **Set** options.

## Questions & Answers

**Q: What makes Thorne supplements high quality?**
A: Thorne produces high-quality supplements through rigorous testing, well-researched ingredient sourcing, and strict manufacturing standards. We avoid unnecessary additives, binders, and fillers that may interfere with nutrient absorption.

**Q: How does Thorne test its supplements for quality?**
A: To confirm the purity of our ingredients, the potency of our formulas, and the absence of all contaminants, we carry out a minimum of four rounds of testing on every product we produce. 100+ Thorne employees are dedicated to ensuring quality.

**Q: Are Thorne supplements clinically Reviewed and safe?**
A: Thorne partners with researchers and conducts clinical trials to support the efficacy of our products. Our team of doctors and medical experts substantiate each ingredient in every formula based on extensive clinical research and medical literature.

**Q: Why are Thorne products more expensive than other supplements?**
A: When it comes to the health of our customers, we never settle. Thorne products may be priced higher than some others because of our commitment to quality at every step. We don’t simply meet the standard in dietary supplements — we set the standard.

**Q: Where are Thorne supplements made and where are the ingredients sourced from?**
A: Located in South Carolina, Thorne manufactures supplements in the USA using globally sourced ingredients. When it comes to ingredient sourcing, we seek out only the highest-quality ingredients, selecting each one for its purity and effectiveness.

## Customer Reviews

### ⭐⭐⭐⭐⭐ MTHFR
*by J***N on 12 October 2025*

High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, I’m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues.

### ⭐⭐⭐⭐⭐ Just what the doctor ordered!
*by L***. on 25 February 2025*

Recently I found out I’m anemic and distant to go on medication so I did my research and found this to have all the things I need.

### ⭐⭐⭐⭐⭐ Love!
*by A***N on 22 September 2025*

Love! It’s high quality, easy to take, and has really helped lower my homocysteine levels as recommended by my doctor. I appreciate that it uses active forms of B vitamins like 5-MTHF for better absorption. Thorne is such a trusted, clean brand, which gives me extra confidence in what I’m taking. I feel more balanced and energized since adding it to my routine—definitely a product I’ll keep using!

## Frequently Bought Together

- THORNE Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules
- THORNE Magnesium CitraMate - Magnesium Supplement with Citrate-Malate - Support Heart, Skeletal Muscles, Cardiac, Lung Function, and Bone Density* - Gluten-Free, Dairy-Free, Soy-Free - 90 Capsules
- THORNE Vitamin D-5000 - Vitamin D3 Supplement - Support Healthy Bones, Teeth, Muscles, Cardiovascular, and Immune Function* - NSF Certified for Sport - Dairy-Free, Soy-Free - 60 Capsules

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*Product available on Desertcart India*
*Store origin: IN*
*Last updated: 2026-07-01*