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🐾 Clear ears, happy pets—because they deserve the best care!
Zymox Advanced Formula Otic Plus is a 1.25oz enzymatic ear solution for dogs and cats that combines the LP3 Enzyme System with 1% Hydrocortisone to effectively clear biofilms, soothe itching, and reduce redness. Safe for all life stages, it requires no pre-cleaning and offers a natural, vet-trusted alternative for managing mild ear irritations.






































| Customer Reviews | 4.7 out of 5 stars 14,523 Reviews |
Y**I
Fast Relief, Clean Application, No Strong Smell
My dog had been scratching one ear a lot, and it was getting hard to ignore. I wanted to try something at home first before going to the vet, so I gave this a shot. The bottle is simple and easy to handle, and the applicator tip helps keep things clean when applying it. The liquid itself is clear, slightly thick (not watery), and doesn’t really have a noticeable odor, which I liked because it didn’t bother my dog at all. After using it as directed, I noticed a difference pretty quickly. By the second use, he had already stopped scratching so much and seemed a lot more comfortable. That was honestly the biggest thing for me. What stood out is how clean the application feels (no mess), the texture of the product, and that it doesn’t have a strong scent. It also seems gentle enough, since my dog didn’t react negatively and stayed calm during use. One small thing is that you still have to apply it carefully, especially if your dog moves a lot. Seeing him relaxed again and not constantly scratching made a big difference. I’d definitely keep this on hand in case it happens again.
J**R
Amazing product
I just wanna say this worked amazing on my pit bulls ears. My poor baby has had on going ear infections going from one ear to another. We have tried so many creams, drop, all that you can think of and some would help for a short while then the irritation would come back again. Within 3 days of use the redness, irritation and infection is gone. No more endless nights of ear shaking and scratching! Was very skeptical at first because of the price, but I will say it’s worth it money 100%
A**R
Best solution for dogs' itchy ear
My dog flapped his ears and used his paws to scratch his ears for about week time. I realized that there was something discomforting in his ears and I search this product. I applied it to my dog the first night and I can see the efficacy in the first night and continue the second night to apply the product to my dog's ear, then I did not see my dog scratch the ears any more. I think the product works perfect for the itchy ears. It is easy to apply without much discomfort, and no scent at all.
E**A
"Visible results from the first use, recommended"
I bought Zymox Plus for my dog after I had a strong irritation in my ears caused by a talc I used previously to clean and remove hairs from the ear canal. That product caused a pretty strong reaction, with inflammation, redness and secretion, which worried me a lot. I decided to try Zymox Plus and, from the first use, I noticed an improvement. The inflammation has been going down, the redness has decreased and my dog looks much more comfortable and calm. I have also noticed less discomfort and improvement in ear cleaning. In my personal experience, it has been a very useful product to help in the recovery and relief of the discomfort of my pet. I recommend it for similar cases, always observing the evolution of the animal and consulting the veterinarian if necessary.
K**E
Works well
My dog was visibly more comfortable after 36 hours, once I applied the ear drops. It didn’t smell, and was easy enough to apply.
T**.
Lifesaver!!
Absolutely phenomenal stuff!!! I'm SO thankful I came across this product, it has saved my poor cat from a very stubborn ear infection that was causing him quite some distress. Even better, I saved hundreds in a vet visit and having to put my cat through the wringer even further. Being a rescue, he HATES going in cat carriers. He gets violent, needs to be sedated, and inevitably soils himself every time. I didn't want to put him (or myself) through that if I could avoid it. I thankfully came across this! His ear was very itchy, red, and irritated. After starting Zymox, I saw notable improvement within a day of use, with significantly reduced redness and crusty discharge! Now on day 6, his ear is almost completely back to normal! No redness, very minimal crust left. I am following the instructions and will be using the product for a full 7 days. Although he only needs one more dose, I think I will give him an extra day or two just to be sure. The product itself is very goopy and sticky, which has helped reduce mess given most of it stays put in his ear where it should be. No bad odor either! I also really like not having to pre-clean my poor boy's ear, he's already not thrilled as it is. Although a bit more expensive than other ear solutions and a smaller bottle, this one is well worth the cost. I super recommend this as a last resort at home before dropping the Big $$$ and tons of stress at the vet!
L**S
Very Effective
My dog was miserable until we tried these ear drops. She gets instant relief. And she doesn’t run away and hide when she sees you getting it to put in her ears 👂. Very thick and not thin like water. She’s not scratching at her ears anymore and her ears doesn’t smell anymore .
A**R
Great Product
I’ve tried different products and this is the first product that works. It cleaned out my dog’s ears and he is not itching and scratching as much. The infection has significantly gotten better.
J**S
Great product. Solved my dog’s ear problem quickly.
Wow! My dog had what I interpreted as excessive wax build up in his ear. He’s a feisty little guy and I could not get on top of it with mere cleaning and hair trimming. With a yeasty smell I turned to this product. The debris that came out of his ear was phenomenal, and now he is irritation free with a very clean ear canal. This product is highly recommended.
A**R
Cures ear infections at a low price
I haven’t had to go to the vet and pay hundreds of dollars for things to fix her ear infections since we got this stuff. I have a Chinese shar pei so it’s really common for them to get ear infections. This stuff is thick and doesn’t go everywhere, travels thru their ear and then you just wipe the excess. It’s great!
J**I
Excellent
Excellent product as describe
G**S
great product , great service
great product , seems to be working fine
B**Y
Cat yeasty ears
Had tried numerous different ways & products to rectify my cat’s yeasty ears which was giving her great irritation. Came across Zymox as a suggestion, applied once a day for 7 days- Problem solved immediately after one weeks use.! Even now a few weeks later she is irritation free and her ears are clear of black debris. Highly recommended.
Trustpilot
1 month ago
2 weeks ago